Advice, Knowledge center, scientific article

Revolutionizing Poultry Health: EXOVET’s Proven Systemic Fluralaner for Complete Red Mite Eradication in Layers and Breeders

Comprehensive Guide to EXOVET (Fluralaner Oral Solution) for Red Mite Control in Layers and Breeders

Poultry red mite (Dermanyssus gallinae) remains a pervasive ectoparasite affecting commercial layer and breeder flocks worldwide. These blood-feeding mites cause significant stress, anemia, reduced egg production, compromised fertility, and economic losses. Effective, safe, and practical control is paramount for sustainable poultry health management.

At Mobedco, we bring you EXOVET—a scientifically validated, fluralaner-based oral solution that offers systemic, long-lasting, and welfare-friendly red mite control through drinking water administration.


Understanding the Challenge: Red Mite Infestations in Poultry

Red mites are nocturnal ectoparasites feeding on bird blood primarily at night. Their presence results in:

  • Chronic blood loss → anemia, pale combs, decreased productivity

  • Stress and irritation → restlessness, feather pecking, reduced feed intake

  • Secondary infections due to skin damage and immunosuppression

  • In breeders: lower fertility, hatchability, and impaired mating behavior

Traditional acaricides like sprays and powders often suffer from incomplete efficacy due to poor penetration, mite hiding behavior, and emerging resistance.


EXOVET’s Active Ingredient: Fluralaner

EXOVET contains fluralaner, a systemic acaricide belonging to the isoxazoline chemical class, acting via selective inhibition of arthropod ligand-gated chloride channels (GABA- and glutamate-gated), causing rapid neuromuscular disruption and mite death.

Why Fluralaner Is a Game-Changer:

  • Systemic action: After oral administration, fluralaner circulates in the blood, killing mites feeding on treated birds. This eliminates the need to spray the environment or handle birds directly.

  • Rapid onset: Mite mortality begins within 4 hours post-treatment.

  • Long-lasting protection: Two doses spaced 7 days apart maintain >90% mite control for months.

  • Effective against resistant populations: Fluralaner’s unique mode of action provides efficacy even where mites have developed resistance to older acaricides.


Recommended Dosage and Administration Protocol

ParameterDetails
Active IngredientFluralaner
Product NameEXOVET Oral Solution
Target SpeciesLayer and breeder hens
Dosage0.5 mg/kg body weight
Administration RouteDrinking water
Treatment ScheduleTwo doses: Day 0 and Day 7
Water RestrictionProvide medicated water exclusively during treatment days (at least 6 hours)

Practical Tips:

  • Restrict access to non-medicated water during treatment to ensure correct dosage intake.

  • Prepare fresh medicated water for each dose to maintain drug stability.

  • Monitor water consumption during treatment days to confirm adequate dosing.


Scientific Evidence Supporting EXOVET

Safety Profile

  • Multiple studies have confirmed the high safety margin of fluralaner in layers and breeders.

  • Overdosing studies (up to 5× the recommended dose) showed no adverse clinical effects, no impact on egg quality, weight, or shell integrity, and no organ pathology.

  • Fluralaner does not require an egg withdrawal period, making it practical for commercial production.

Residue and Withdrawal Considerations

  • Fluralaner is lipophilic, concentrating primarily in egg yolk.

  • Pharmacokinetic studies indicate rapid depletion after oral dosing, with residue levels declining below regulatory maximum residue limits (MRLs) within approximately 7 days.

  • This supports EXOVET’s “no withdrawal” label under recommended use but emphasizes adherence to dosing schedules for export compliance.

Field Efficacy

  • Field trials across multiple countries demonstrated 95-99.8% mite population reductions within 3 days, rising to near-total elimination by Day 9.

  • Benefits extended to improved egg production (+0.9% to +12.6%) and breeder fertility.

  • Treated flocks showed reduced stress behaviors and improvements in hematological parameters such as red blood cell counts.

Impact on Mite Reproductive Cycle

  • EXOVET disrupts mite reproduction by inhibiting egg laying for at least 19 days post-treatment, preventing population rebound and reducing the need for frequent interventions.


Integrating EXOVET into Your Poultry Health Program

Benefits for Producers:

  • Ease of use: Administered via drinking water—no need for stressful handling or spraying.

  • Saves labor and downtime: No coop emptying or cleaning required during treatment.

  • Welfare-friendly: Reduces mite-induced irritation and stress, improving bird comfort.

  • Sustainable approach: Helps manage acaricide resistance with a novel mode of action.

Recommended Best Practices:

  • Combine EXOVET treatment with enhanced biosecurity and environmental hygiene.

  • Monitor mite populations regularly to time treatment before severe infestations develop.

  • Use in rotation with other control methods as part of an Integrated Pest Management (IPM) strategy.


Frequently Asked Questions

Q: Can EXOVET be used in all poultry housing systems?
Yes, EXOVET is suitable for cage, aviary, and free-range systems.

Q: Is EXOVET safe during peak egg production?
Yes, it has been tested and shown safe with no egg withdrawal.

Q: What if water consumption is low during treatment?
Ensure medicated water is the only water source and monitor consumption closely.


Conclusion

EXOVET (fluralaner oral solution) provides poultry producers with an innovative, highly effective, and safe tool for managing red mite infestations in layers and breeders. Its systemic mode of action, ease of administration, and long-lasting protection make it a valuable component of modern poultry health programs.


Contact Mobedco Today

For further information, technical support, or to order EXOVET, please contact Mobedco or your local authorized distributor. Protect your flock with the proven power of EXOVET.

Exovet (Oral Solution)

Leave a Reply

Your email address will not be published. Required fields are marked *