Sulphaprim
Sulphaprim Injection combines Sulphadiazine-Na and Trimethoprim, offering broad-spectrum antibacterial action against Gram-positive and Gram-negative organisms like E. coli, Staphylococci, Streptococci, and Salmonella. Ideal for horses, cattle, dogs, and cats, it treats respiratory, urogenital, and alimentary tract infections, as well as neonatal diarrhea, salmonellosis, mastitis, and secondary bacterial infections.
Description
Each 1 ml contains:
Sulphadiazine-Na 200 mg
Trimethoprim 40 mg
Sulphaprim is indicated in the treatment of systemic infections caused by or associated with organisms sensitive to the Trimethoprim: Sulfadiazine combination. The in vitro spectrum of activity includes both Gram positive and Gram negative organisms including:
Actinobacilli , Actinomycae , Bordetella spp. , Brucella , Corynebacteriea , Escherichia coli , Haemophilus spp. , Klebsiella spp. , Pasturella spp. , Pneumococci , Proteus , Salmonella spp. , Staphylococci , Streptococci .
Sulphaprim is indicated for use in horses, cattle, dogs and cats for the treatment of acute, subacute and chronic bacterial infections sensitive to trimethoprim/sulphadiazine therapy such as: Bacterial infections of the respiratory tract, including rhinitis, pneumonia, bronchitis and in bacterial infections secondary to viral diseases such as viral pneumonia or mycoplasma infections. Urogenital tract infections, including cystitis, vaginitis, urethritis, nephritis and metritis.
Alimentary tract infections, including neonatal diarrhea and salmonellosis. Other infections, such as foul-in-the-foot, severe mastitis, infections of eye, ear or mouth .
Cattle: the recommended dose rate is 15 mg of active ingredients per kg bodyweight (1 ml per 16 kg bodyweight) once by intramuscular or slow intravenous injections, but in severe infections it may be repeated daily until 2 days after symptoms resolve up to maximum of 5 days.
Sulphaprim may be administered by intravenous injection when rapid blood levels of trimethoprim and Sulfadiazine are required.
Horses: the recommended dose rate is 15 mg of active ingredients per kg bodyweight (1 ml per 16 kg bodyweight), by slow intravenous injection.
Dogs and Cats: the recommended dose rate is 30 mg of active ingredients per kg bodyweight (1 ml per 8 kg bodyweight), by subcutaneous injection only.
The recommended site in dogs is the loose skin at the top of the neck.
A single injection may be sufficient in uncomplicated conditions, but in severe infections it may be repeated daily for up to 5 days until 2 days after the symptoms have resolved.
-Should not be given by routes other than those recommended.
-Not to be administered intraperitoneally.
-Do not use in animals with known sulphonamide sensitivity, severe liver parenchymal damage or blood dyscrasis.
-Do not administer to horses exhibiting drug-induced cardiac arrhythmias .
-Milk for human consumption may only be taken from cattle after 48 hours from the last treatment.
-Cattle may be slaughtered for human consumption only after 12 days from the last treatment.
Store in a dry and dark place at temperature below 30˚C.
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